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Group A Meningococcal Polysaccharide Vaccines


    Group A Meningococcal polysaccharide vaccine is a purified capsular polysaccharide antigen extracted from the culture of Neisseria meningitides group A and lyophilized after addition of an appropriate stabilizer. It is used to prevent epidemic cerebrospinal meningitis caused by Neisseria meningitides group A.

1. Drug name
    Adopted name: Group A Meningococcal Polysaccharide Vaccine
2. Eligible
    Children aged of 6 months to 15 years.
3. Function and use
    The vaccine can induce humoral immune response in recipients following immunization. It is used to prevent epidemic cerebrospinal meningitis caused by Neisseria meningitides group A.
4. Specifications
    There is 150 ug or 300 ug of polysaccharide per container. Each single human dose contains 30 ug of polysaccharide.
5. Administration and dosage
(1)      Open the container and reconstitute vaccine with the accompanying diluent as stated on the label. Shake and inject immediately.
(2)      The vaccine should be injected s. c. at deltoid insertion area of the lateral upper arm at a dosage of not less than 30 ug of polysaccharide (in 0.2 ml or 0.5 ml).
(3)      The primary immunization consisting of two injections for children shall begin at 6 months of age, at an interval of 3 months. One booster shall be given to the children at 3 years of age or older before the epidemic season.
(4)      Revaccinations may be given every 3 years, if needed. The vaccine may be administered to other age group for emergent vaccination during epidemic.
6. Adverse reactions
    The adverse reactions are mild. Transient low fever occurs occasionally. Slight tenderness at injection site may occur, which can be relieved spontaneously.
7. Validity period
    24 months.
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